"NRG1" Related Products

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Recombinant Human NRG1 Protein, His-tagged

Cat.No.: NRG1-679H
Product Overview: Recombinant Human NRG1 (Accession # NP_039253) Met1-Glu296, Leu117-Glu296 & Ala162-Glu296, fused with a C-terminal 6-His tag, was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.
Source: Baculovirus Sf21 Insect Cells
Species: Human
Tag: His
Predicted N Terminal: Met1, Leu117 & Ala162
Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Bio-activity: Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.The ED50 for this effect is typically 1 - 5 ng/mL.
Molecular Mass: Recombinant Human NRG1, His-tagged has a calculated MW of 33 kDa. In SDS-PAGE migrates as 25-45 kDa, reducing conditions.
Protein length: Met1-Glu296, Leu117-Glu296 & Ala162-Glu296
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: NRG1 neuregulin 1 [ Homo sapiens ]
Official Symbol: NRG1
Synonyms: NRG1; neuregulin 1; HGL; pro-neuregulin-1, membrane-bound isoform; GGF; HRG; NDF; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator); ARIA; GGF2; HRG1; HRGA; SMDF; MST131;
Gene ID: 3084
mRNA Refseq: NM_001159995
Protein Refseq: NP_001153467
MIM: 142445
UniProt ID: Q02297
Chromosome Location: 8p21-p12

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