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Recombinant Human ARTN

Cat.No.: ARTN-801H
Product Overview: Recombinant Human ARTN (Accession # NP_476432) Ala108-Gly220, fused with , was produced in E. coli.
Source: E. coli
Species: Human
Predicted N Terminal: Ala108
Form: Lyophilized from a 0.2 µm filtered solution in HCl with BSA as a carrier protein.
Bio-activity: Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells.The ED50 for this effect is typically 4-16 ng/mL.Measured by its binding ability in a functional ELISA.Immobilized Recombinant Human GFR alpha -3/GDNF R alpha -3 Fc Chimera at 1 µg/mL (100 µL/well) can bind Recombinant Human Artemin with an apparent Kd <1 nM.
Molecular Mass: Recombinant Human ARTN has a calculated MW of 12 kDa (monomer). In SDS-PAGE migrates as 12 kDa, reducing conditions.
Protein length: Ala108-Gly220
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: ARTN artemin [ Homo sapiens ]
Official Symbol: ARTN
Synonyms: ARTN; artemin; ENOVIN; EVN; NBN; neublastin; neurotrophic factor;
Gene ID: 9048
mRNA Refseq: NM_001136215
Protein Refseq: NP_001129687
MIM: 603886
UniProt ID: Q5T4W7
Chromosome Location: 1p33-p32

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