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Recombinant Human DAND5

Cat.No.: DAND5-837H
Product Overview: Recombinant Human DAND5 (Accession # NP_689867) Arg23-Ala189, fused with an N-terminal Met, was produced in E. coli.
Source: E. coli
Species: Human
Predicted N Terminal: Met
Form: Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Bio-activity: Measured by its ability to inhibit BMP-4-induced activity in MC3T3-E1 mouse preosteoblast cells.The ED50 for this effect is typically 0.15 - 0.75 µg/mL in the presence of 50 ng/mL of rhBMP-4.
Molecular Mass: Recombinant Human DAND5, Met-tagged has a calculated MW of 18.2 kDa (monomer).
Protein length: Arg23-Ala189
Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name: DAND5 DAN domain family member 5, BMP antagonist [ Homo sapiens (human) ]
Official Symbol: DAND5
Synonyms: SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3; DAN domain family member 5; DAN domain family member 5; DAN domain family, member 5; cerberus 2; cerberus-like 2; cerberus-like protein 2; cerl-2; cysteine knot superfamily 1, BMP antagonist 3; gremlin-3
Gene ID: 199699
mRNA Refseq: NM_152654.2
Protein Refseq: NP_689867.1
MIM: 609068
UniProt ID: Q8N907
Chromosome Location: 19p13.

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