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Active Recombinant Mouse Dner Protein, Fc Chimera

Cat.No. : Dner-838M
Product Overview : Recombinant Mouse Dner (Accession # NP_690879), fused with , was produced in Mouse myeloma cell line, NS0-derived.
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  • Gene Information
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Source : Mammalian cells
Species : Mouse
Tag : Fc
Predicted N Terminal : Ala26
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its ability to inhibit Pleiotrophin-induced neurite outgrowth of E16-E18 rat embryonic cortical neurons.When 4 x 10^4 neurons/well are added to 96-well plate containing serial dilutions of Recombinant Mouse DNER Fc Chimera and immobilized Recombinant Mouse Pleiotrophin/PTN (1 µg/mL), neurite outgrowth is significantly inhibited in a dose dependent manner. The ED50 for this effect is typically 0.5 - 2.5 µg/mL.
Molecular Mass : Recombinant Mouse Dner, Fc Chimera has a calculated MW of 91.4 kDa (reduced). In SDS-PAGE migrates as 140-160 kDa, reducing conditions.
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Gene Name : Dner delta/notch-like EGF-related receptor [ Mus musculus ]
Official Symbol : Dner
Synonyms : DNER; delta/notch-like EGF-related receptor; delta and Notch-like epidermal growth factor-related receptor; transmembrane protein Bet; brain EGF repeat-containing transmembrane protein; BET; Bret; A930026D19Rik; MGC39059;
Gene ID : 227325
mRNA Refseq : NM_152915
Protein Refseq : NP_690879
MIM :

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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