Recombinant Human CXCL17 protein CXCL17-872H

Recombinant Human CXCL17 protein

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Recombinant Human CXCL17 protein

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Cat.No. : CXCL17-872H
Product Overview : Recombinant Human CXCL17 protein was expressed in Escherichia coli.
Description : The protein encoded by this gene is a mucosal chemokine that attracts immature dendritic cells and blood monocytes to the lungs. The encoded protein also promotes tumorigenesis through an angiogenic activity. Finally, this protein exhibits strong antimicrobial activity against E. coli, S. aureus, Salmonella, P. aeruginosa, and C. albicans. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4, with 3 % Trehalose.
Bio-activity : Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/mg.
Molecular Mass : Approximately 11.5 kDa, a single non-glycosylated polypeptide chain containing 98 amino acids.
Protein length : 98
AA Sequence : SSLNPGVARGHRDRG QASRRWLQEGGQECE CKDWFLRAPRRKFMT VSGLPKKQCPCDHFK GNVKKTRHQRHHRKP NKHSRACQQFLKQCQ LRSFALPL
Endotoxin : Less than 0.1 EU/μg of rHuVCC-1/CXCL17 as determined by LAL method.
Purity : >96% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
SDS-PAGE of CXCL17-872H :

Gene Name : CXCL17
Official Symbol : CXCL17
Synonyms : CXCL17; chemokine (C-X-C motif) ligand 17; VEGF co-regulated chemokine 1; Dcip1; DMC; UNQ473; VCC1; C-X-C motif chemokine 17; dendritic cell and monocyte chemokine-like protein; VCC-1; MGC138300;
Gene ID : 284340
mRNA Refseq : NM_198477
Protein Refseq : NP_940879
MIM : 611387
UniProt ID : Q6UXB2

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