| Cat.No. : |
LRP6-1040H |
| Product Overview : |
Recombinant Human LRP6 (Accession # O75581), fused with , was produced in Mouse myeloma cell line, NS0-derived. |
| Source : |
Mammalian cells |
| Species : |
Human |
| Tag : |
Fc |
| Predicted N Terminal : |
Ala20 |
| Form : |
Lyophilized from a 0.2 µm filtered solution in PBS. |
| Bio-activity : |
Measured by its binding ability in a functional ELISA.rhLRP-6/Fc Chimera binds rhDkk-1, biotin with an apparent KD < 25 nM.Biotinylated rmWnt-3a immobilized on a streptavidin-coated plate at 1 µg/mL can bind rhLRP-6/Fc Chimera with a linear range of 0.2 - 10 µg/mL. Optimal concentrations should be determined by each laboratory for each application. |
| Molecular Mass : |
Recombinant Human LRP6, Fc Chimera has a calculated MW of 180 kDa (monomer). In SDS-PAGE migrates as 200 kDa, reducing conditions. |
| Purity : |
>80%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Storage : |
Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
| Reconstitution : |
Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.