Recombinant Human LRP6 Protein, Fc Chimera

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Recombinant Human LRP6 Protein, Fc Chimera

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Cat.No. : LRP6-1040H
Product Overview : Recombinant Human LRP6 (Accession # O75581), fused with , was produced in Mouse myeloma cell line, NS0-derived.
Source : Mammalian cells
Species : Human
Tag : Fc
Predicted N Terminal : Ala20
Form : Lyophilized from a 0.2 µm filtered solution in PBS.
Bio-activity : Measured by its binding ability in a functional ELISA.rhLRP-6/Fc Chimera binds rhDkk-1, biotin with an apparent KD < 25 nM.Biotinylated rmWnt-3a immobilized on a streptavidin-coated plate at 1 µg/mL can bind rhLRP-6/Fc Chimera with a linear range of 0.2 - 10 µg/mL. Optimal concentrations should be determined by each laboratory for each application.
Molecular Mass : Recombinant Human LRP6, Fc Chimera has a calculated MW of 180 kDa (monomer). In SDS-PAGE migrates as 200 kDa, reducing conditions.
Purity : >80%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
Reconstitution : Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Gene Name : LRP6 low density lipoprotein receptor-related protein 6 [ Homo sapiens ]
Official Symbol : LRP6
Synonyms : LRP6; low density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6; LRP-6; ADCAD2; FLJ90062; FLJ90421;
Gene ID : 4040
mRNA Refseq : NM_002336
Protein Refseq : NP_002327
MIM : 603507
UniProt ID : O75581
Chromosome Location : 12p13.2
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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