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Active Recombinant Human TNFRSF10D, Fc-tagged

Cat.No. : TNFRSF10D-563H
Product Overview : The recombinant human DcR2-Fc fusion is expressed as a 382 amino acid protein consisting of Ala56 - Pro209 region of DcR2 (UniProt accession #Q9UBN6) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
  • Specification
  • Gene Information
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Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier and preservative free)
Bio-activity : Binds to its ligand human TRAIL and inhibits TRAIL-mediated signaling activity including TRAIL--induced cytotoxicity
Molecular Mass : Calculated molecular mass (kDa): 42.1; Estimated by SDS-PAGE under reducing condition (kDa): 50-60
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain [ Homo sapiens ]
Official Symbol : TNFRSF10D
Synonyms : TNFRSF10D; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; tumor necrosis factor receptor superfamily member 10D; CD264; DcR2; TRAILR4; TRUNDD; TRAIL receptor 4; decoy receptor 2; decoy with truncated death domain; TNF receptor-related receptor for TRAIL; TRAIL receptor with a truncated death domain; TNF-related apoptosis-inducing ligand receptor 4; DCR2; TRAIL-R4;
Gene ID : 8793
mRNA Refseq : NM_003840
Protein Refseq : NP_003831
MIM : 603614
UniProt ID : Q9UBN6
Chromosome Location : 8p21
Pathway : Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Direct p53 effectors, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem;
Function : TRAIL binding; binding; receptor activity; transmembrane signaling receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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