Active Recombinant Human THY1, Fc-tagged

• Cat.No.: THY1-586H
• Product Overview: The recombinant human CD90-Fc fusion is expressed as a 348 amino acid protein consisting of Gln20 - Lys129 region of CD90 (Uniprot Accession #P04216) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.

Specification

• Source: Human cells
• Species: Human
• Tag: Fc
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier and preservative free).
• Bio-activity: Immobilized CD90-Fc protein supports the adhesion of human neutrophils with an ED50 typically between 0.5 - 2.5 μg/mL
• Molecular Mass: Calculated molecular mass (kDa): 39.2; Estimated by SDS-PAGE under reducing condition (kDa): 55-60
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: THY1 Thy-1 cell surface antigen [ Homo sapiens ]
• Official Symbol: THY1
• Synonyms: THY1; Thy-1 cell surface antigen; thy-1 membrane glycoprotein; CD90; CDw90; thy-1 antigen; Thy-1 T-cell antigen; FLJ33325
• Gene ID: 7070
• mRNA Refseq: NM_006288
• Protein Refseq: NP_006279
• MIM: 188230
• UniProt ID: P04216
• Chromosome Location: 11q23.3
• Pathway: IL4-mediated signaling events, organism-specific biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; amb2 Integrin signaling, organism-specific biosystem
• Function: GPI anchor binding; Rho GTPase activator activity; enzyme binding; integrin binding; protein binding; protein kinase binding