"SPTAN1" Related Products


Recombinant Human SPTAN1, MYC/DDK-tagged

Cat.No.: SPTAN1-479H
Product Overview: Recombinant Human SPTAN1, transcript variant 1, fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.
Description: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Source: HEK293 Cells
Species: Human
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 284.9 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: SPTAN1 spectrin, alpha, non-erythrocytic 1 [ Homo sapiens ]
Official Symbol: SPTAN1
Synonyms: NEAS; EIEE5; SPTA2; spectrin alpha chain, non-erythrocytic 1; alpha-II spectrin; alpha-fodrin; fodrin alpha chain; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit
Gene ID: 6709
mRNA Refseq: NM_001130438
Protein Refseq: NP_001123910
MIM: 182810
UniProt ID: Q13813
Chromosome Location: 9q34.11
Pathway: Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Axon guidance, organism-specific biosystem
Function: actin binding; calcium ion binding; protein binding

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