"SPTAN1" Related Products


Recombinant Human SPTAN1, His-tagged

Cat.No.: SPTAN1-32H
Product Overview: Recombinant Human SPTAN1 (Glu922~Ala1043) fussed with His tag at N-terminal was expressed in E. coli.
Description: Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Source: E. coli
Species: Human
Tag: His
Molecular Mass: 15.1kDa
Purity: > 95%
Applications: SDS-PAGE, Western Blot, ELISA, Immunoprecipitation
Usage: For Research Use Only
Storage: Can be stored at 4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Gene Name: SPTAN1 spectrin, alpha, non-erythrocytic 1 [ Homo sapiens ]
Official Symbol: SPTAN1
Synonyms: NEAS; EIEE5; SPTA2; spectrin alpha chain, non-erythrocytic 1; alpha-II spectrin; alpha-fodrin; fodrin alpha chain; spectrin, non-erythroid alpha chain; spectrin, non-erythroid alpha subunit
Gene ID: 670
mRNA Refseq: NM_001130438
Protein Refseq: NP_001123910
MIM: 182810
UniProt ID: Q13813
Chromosome Location: 9q34.11
Pathway: Caspase cascade in apoptosis, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; Developmental Biology, organism-specific biosystem
Function: protein binding; protein heterodimerization activity; spectrin binding

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