Recombinant Mouse Sptan1, His-tagged Sptan1-33M

Recombinant Mouse Sptan1, His-tagged

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Recombinant Mouse Sptan1, His-tagged

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Cat.No. : Sptan1-33M
Product Overview : Recombinant Mouse Sptan1 (Arg402~Glu599) fussed with His tag at N-terminal was expressed in E. coli.
Description : The spectrins are a family of widely distributed cytoskeletal proteins which are involved in actin crosslinking. The protein enocoded by this gene is a spectrin alpha-chain which heterodimerizes with tissue-specific beta-chains. It is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Source : E. coli
Species : Mouse
Tag : His
Molecular Mass : 24.8kDa
Purity : > 95%
Applications : SDS-PAGE, Western Blot, ELISA, Immunoprecipitation
Usage : For Research Use Only
Storage : Can be stored at 4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Gene Name : Sptan1 spectrin alpha, non-erythrocytic 1 [ Mus musculus ]
Official Symbol : Sptan1
Synonyms : Spna2; Spna-2; 2610027H02Rik; spectrin alpha chain, non-erythrocytic 1; alpha-II spectrin; alpha-fodrin; alpha-spectrin 2, brain; fodrin alpha chain; spectrin alpha 2; spectrin alpha chain, brain; spectrin, non-erythroid alpha chain
Gene ID : 20740
mRNA Refseq : NM_001076554
Protein Refseq : NP_001070022
Chromosome Location : 2 B; 2 20.93 Cm
Pathway : Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Axon guidance, organism-specific biosystem
Function : actin binding; calcium ion binding; calmodulin binding

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