Active Recombinant Human XCL1, MIgG2a Fc-tagged
Cat.No. : | XCL1-160H |
Product Overview : | The extracellular domain of human XCL1 (AAH70309.1) (Val22-Gly114) is fused to the N-terminus of the Fc region of mouse lgG2a. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunologicalresponses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokinesubfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specificallychemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome1 |
Source : | CHO cell |
Species : | Human |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to chemoattract BaF3 mouse proB cells. |
Molecular Mass : | 36KDa (monomer) |
AA Sequence : | Val22-Gly114 |
Endotoxin : | <0.06 eu/μg as determined by lal>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
References : | 1.Expression and function of the C-class chemokine lymphotactin (XCL1) in Wegener"s granulomatosis. 2.Interconversion between two unrelated protein folds in the lymphotactin native state. |
Gene Name : | XCL1 chemokine (C motif) ligand 1 [ Homo sapiens ] |
Official Symbol : | XCL1 |
Synonyms : | XCL1; chemokine (C motif) ligand 1; LTN, SCYC1, small inducible cytokine subfamily C, member 1 (lymphotactin); lymphotactin; ATAC; LPTN; SCM 1; SCM 1a; SCM-1-alpha; lymphotaxin; cytokine SCM-1; c motif chemokine 1; XC chemokine ligand 1; single cysteine motif 1a; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin); LTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a; |
Gene ID : | 6375 |
mRNA Refseq : | NM_002995 |
Protein Refseq : | NP_002986 |
MIM : | 600250 |
UniProt ID : | P47992 |
Chromosome Location : | 1q24.2 |
Pathway : | Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; G alpha (q) signalling events, organism-specific biosystem; |
Function : | chemokine activity; chemokine receptor binding; chemokine receptor binding; protein homodimerization activity; |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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