Active Recombinant Rat Hmgb1 protein

• Cat.No.: Hmgb1-18R
• Product Overview: Recombinant Rat Hmgb1 consisted of 215 amino acid residues was expressed in E. coli.

Specification

• Species: Rat
• Source: E.coli
• Tag: Non
• Description: heparin binding protein that facilitates neurite outgrowth.
• Form: 50 mM HEPES buffer pH 7.9, 500 mM NaCl, 0.5 mM DTT.
• Bio-activity: This preparation has low cytokine activity, but is fully active as a DNA binding protein or as an antigen.
• Molecular Mass: Has a calculated molecular mass of approximately 24.8 kDa. It migrates at a position of approximately 30 kD in SDS-PAGE gels, possibly because of the unusual number of positively charged amino acids it contains.
• AA Sequence: MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEDD EEDEEDEEEE EEEEDEDEEE DDDDE
• Purity: The purified protein is >95% homogeneous (electrophoresis and mass spectrometry).
• Storage: We advise to keep the product frozen at -20 centigrade.

Gene Information

• Gene Name: Hmgb1 high mobility group box 1 [ Rattus norvegicus ]
• Official Symbol: Hmgb1
• Synonyms: Hmg1; Ac2-008; high mobility group protein B1; HMG-1; amphoterin; heparin-binding protein p30; high mobility group 1; high mobility group protein 1
• Gene ID: 25459
• mRNA Refseq: NM_012963
• Protein Refseq: NP_037095
• UniProt ID: P63159
• Chromosome Location: 12p11
• Pathway: Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem
• Function: 5S rRNA binding; DNA binding; DNA binding, bending