Recombinant Human YWHAQ protein, MYC/DDK-tagged YWHAQ-123H

Recombinant Human YWHAQ protein, MYC/DDK-tagged

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Recombinant Human YWHAQ protein, MYC/DDK-tagged

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Cat.No. : YWHAQ-123H
Product Overview : Recombinant Human YWHAQ fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.
Description : This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
Source : HEK293 cells
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 27.6 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta [ Homo sapiens ]
Official Symbol : YWHAQ
Synonyms : 1C5; HS1; 14-3-3; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Gene ID : 10971
mRNA Refseq : NM_006826
Protein Refseq : NP_006817
MIM : 609009
UniProt ID : P27348
Chromosome Location : 2p25.1
Pathway : Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Apoptosis, organism-specific biosystem
Function : protein N-terminus binding; protein binding; protein domain specific binding

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