"PARG" Related Products

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Recombinant Human PARG protein, His-tagged

Cat.No.: PARG-31H
Product Overview: Recombinant Human PARG fussed with His tag was expressed in Sf21 cells.
Description: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.
Source: Insect cells
Species: Human
Tag: His
Form: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol.
Bio-activity: ~100ng is required for poly(ADP-ribose) degradation assays.
Purity: ≥95% (SDS-PAGE)
Notes: After opening, prepare aliquots and store at -80 centigrade. Avoid freeze/thaw cycles.
Stability: Stable for at least 6 months after receipt when stored at -80 centigrade.
Storage: Short Term Storage: -20 centigrade;Long Term Storage: -80 centigrade.
Concentration: Lot dependent (0.2-1.5mg/ml)
Gene Name: PARG poly (ADP-ribose) glycohydrolase [ Homo sapiens ]
Official Symbol: PARG
Synonyms: PARG99; poly(ADP-ribose) glycohydrolase; mitochondrial poly(ADP-ribose) glycohydrolase; poly(ADP-ribose) glycohydrolase 60 kDa isoform
Gene ID: 850
mRNA Refseq: NM_003631
Protein Refseq: NP_003622
MIM: 603501
UniProt ID: Q86W56
Chromosome Location: 10q11.23
Pathway: Base Excision Repair, organism-specific biosystem; DNA Repair, organism-specific biosystem; POLB-Dependent Long Patch Base Excision Repair, organism-specific biosystem
Function: poly(ADP-ribose) glycohydrolase activity

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