Recombinant Human PARG protein, His-tagged


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Recombinant Human PARG protein, His-tagged

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Cat.No. : PARG-31H
Product Overview : Recombinant Human PARG fussed with His tag was expressed in Sf21 cells.
Description : Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG hydrolyzes poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.
Source : Insect cells
Species : Human
Tag : His
Form : Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50mM imidazole and 10% glycerol.
Bio-activity : ~100ng is required for poly(ADP-ribose) degradation assays.
Purity : ≥95% (SDS-PAGE)
Notes : After opening, prepare aliquots and store at -80 centigrade. Avoid freeze/thaw cycles.
Stability : Stable for at least 6 months after receipt when stored at -80 centigrade.
Storage : Short Term Storage: -20 centigrade;Long Term Storage: -80 centigrade.
Concentration : Lot dependent (0.2-1.5mg/ml)
Publication :
Gene Name : PARG poly (ADP-ribose) glycohydrolase [ Homo sapiens ]
Official Symbol : PARG
Synonyms : PARG99; poly(ADP-ribose) glycohydrolase; mitochondrial poly(ADP-ribose) glycohydrolase; poly(ADP-ribose) glycohydrolase 60 kDa isoform
Gene ID : 850
mRNA Refseq : NM_003631
Protein Refseq : NP_003622
MIM : 603501
UniProt ID : Q86W56
Chromosome Location : 10q11.23
Pathway : Base Excision Repair, organism-specific biosystem; DNA Repair, organism-specific biosystem; POLB-Dependent Long Patch Base Excision Repair, organism-specific biosystem
Function : poly(ADP-ribose) glycohydrolase activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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