Recombinant Human PARG Protein, GST-tagged

• Cat.No.: PARG-87H
• Product Overview: Recombinant Human PARG Protein, fused to GST-tag, was expressed in E. coli.

Specification

• Description: Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products. Several transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: GST
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH8.0).
• Molecular Mass: ~68.2 kDa
• AA Sequence: MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRG SGSQKMNHSITMSQEQIASLLANAF FCTFPRRNAKMKSEYSSYPDINFNR LFEGRSSRKPEKLKTLFCYFRRVTE KKPTGLVTFTRQSLEDFPEWERCEK PLTRLHVTYEGTIEENGQGMLQVDF ANRFVGGGVTSAGLVQEEIRFLINP ELIISRLFTEVLDHNECLIITGTEQ YSEYTGYAETYRWSRSHEDGSERDD WQRRCTEIVAIDALHFRRYLDQFVP EKMRRELNKAYCGFLRPGVSSENLS AVATGNWGCGAFGGDARLKALIQIL AAAAAERDVVYFTFGDSELMRDIYS MHIFLTERKLTVGDVYKLLLRYYNE ECRNCSTPGPDIKLYPFIYHAVESC AETADHSGQRTGTAAAS
• Purity: >90%
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.4 mg/ml

Gene Information

• Gene Name: PARG poly(ADP-ribose) glycohydrolase [ Homo sapiens (human) ]
• Official Symbol: PARG
• Synonyms: PARG99
• Gene ID: 8505
• mRNA Refseq: NM_001303486
• Protein Refseq: NP_001290415
• MIM: 603501
• UniProt ID: Q86W56