Recombinant Human TNFRSF14, Fc-tagged, Biotinylated TNFRSF14-624H

Recombinant Human TNFRSF14, Fc-tagged, Biotinylated

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Recombinant Human TNFRSF14, Fc-tagged, Biotinylated

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Cat.No. : TNFRSF14-624H
Product Overview : The recombinant human HVEM-Fc fusion is expressed as a 388 amino acid protein consisting of Leu39 - Ser199 region of HVEM (UniProt accession #Q92956) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its ligands, BTLA/CD272, TNF-β and LIGHT, and inhibits TNF-β- and LIGHT-mediated signaling acitivities including cytotoxicity in L-929 mouse fibroblast cells.
Molecular Mass : Calculated molecular mass (kDa): 42.4; Estimated by SDS-PAGE under reducing condition (kDa): 55-60
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : TNFRSF14 tumor necrosis factor receptor superfamily, member 14 [ Homo sapiens ]
Official Symbol : TNFRSF14
Synonyms : TNFRSF14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); tumor necrosis factor receptor superfamily member 14; ATAR; CD270; herpesvirus entry mediator; HVEA; HVEM; LIGHTR; TR2; CD40-like protein; herpesvirus entry mediator A; herpes virus entry mediator A; tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2;
Gene ID : 8764
mRNA Refseq : NM_003820
Protein Refseq : NP_003811
MIM : 602746
UniProt ID : Q92956
Chromosome Location : 1p36.32
Pathway : Adaptive Immune System, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Immune System, organism-specific biosystem;
Function : protein binding; receptor activity; tumor necrosis factor-activated receptor activity;

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