Recombinant Human IGF2R, Fc-tagged, Biotinylated


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Recombinant Human IGF2R, Fc-tagged, Biotinylated

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Cat.No. : IGF2R-625H
Product Overview : The recombinant human IGF2R-Fc is expressed as a 714 amino acid protein consisting of Met1508 - Leu1992 region of IGF2R (UniProt #P11717, repeat #11-13) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition.
Source : Human cells
Species : Human
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier free & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its ligand IGF2 and inhibits IGF2-mediated signaling activity.
Molecular Mass : Calculated molecular mass 79.2 kDa; estimated by SDS-PAGE under reducing condition 85-90 kDa probably due to glycosylation
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : IGF2R insulin-like growth factor 2 receptor [ Homo sapiens ]
Official Symbol : IGF2R
Synonyms : IGF2R; insulin-like growth factor 2 receptor; cation-independent mannose-6-phosphate receptor; cation independent mannose 6 phosphate receptor; CD222; CIMPR; M6P R; MPR1; MPRI; M6PR; CI-MPR; MPR 300; M6P/IGF2R; IGF-II receptor; M6P/IGF2 receptor; CI Man-6-P receptor; 300 kDa mannose 6-phosphate receptor; insulin-like growth factor II receptor; cation-independent mannose-6 phosphate receptor; M6P-R;
Gene ID : 3482
mRNA Refseq : NM_000876
Protein Refseq : NP_000867
MIM : 147280
UniProt ID : P11717
Chromosome Location : 6q25-q27
Pathway : Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem;
Function : glycoprotein binding; insulin-like growth factor binding; insulin-like growth factor-activated receptor activity; mannose binding; phosphoprotein binding; protein binding; receptor activity; transporter activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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