Active Recombinant Human SIGLEC9, Fc-tagged, Biotinylated

• Cat.No.: SIGLEC9-676H
• Product Overview: The recombinant human CD329-Fc is expressed as a 556 amino acid protein consisting of Gln18 - Gly348 region of CD329 and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition.

Specification

• Source: Human cells
• Species: Human
• Tag: Fc
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
• Bio-activity: Immobilized protein supports the adhesion of human red blood cells. Blocks CD329-binding to its ligand and signaling activity.
• Molecular Mass: Calculated molecular mass (kDa): 61.4; Estimated by SDS-PAGE under reducing condition (kDa): 80-90 (probably due to glycosylation)
• AA Sequence: QTSKLLTMQSSVTVQEGLCVHVPCS FSYPSHGWIYPGPVVHGYWFREGAN TDQDAPVATNNPARAVWEETRDRF HLLGDPHTKNCTLSIRDARRSDAGR YFFRMEKGSIKWNYKHHRLSVNVTA LTHRPNILIPGTLESGCPQNLTCS VPWACEQGTPPMISWIGTSVSPLDP STTRSSVLTLIPQPQDHGTSLTCQV TFPGASVTTNKTVHLNVSYPPQN LTMTVFQGDGTVSTVLGNGSSLSLP EGQSLRLVCAVDAVDSNPPARLSLS WRGLTLCPSQPSNPGVLELPWVHL RDAAEFTCRAQNPLGSQQVYLNVSL QSKATSGVTQGTHTCPPCPAPELLG GPSVFLFPPKPKDTLMISRTPEVT CVVVDVSHEDPEVKFNWYVDGVEVH NAKTKPREEQYNSTYRVVSVLTVLH QDWLNGKEYKCKVSNKALPAPIE KTISKAKGQPREPQVYTLPPSREEM TKNQVSLTCLVKGFYPSDIAVEWES NGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQGNVFSCSVMHEAL HNHYTQKSLSLSPGK
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: SIGLEC9 sialic acid binding Ig-like lectin 9 [ Homo sapiens ]
• Official Symbol: SIGLEC9
• Synonyms: SIGLEC9; sialic acid binding Ig-like lectin 9; sialic acid-binding Ig-like lectin 9; CD329; protein FOAP-9; CDw329; FOAP-9; siglec-9; OBBP-LIKE
• Gene ID: 27180
• mRNA Refseq: NM_001198558
• Protein Refseq: NP_001185487
• MIM: 605640
• UniProt ID: Q9Y336
• Chromosome Location: 19q13.3-q13.4
• Function: sugar binding