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Active Recombinant Mouse Cd274, Fc-tagged, Biotinylated

Cat.No. : Cd274-721M
Product Overview : The recombinant mouse PD-L1/CD274 ECD is expressed as a 458 amino acid protein consisting of Phe19 - Thr238 region of mouse PD-L1/CD274 (UniProt accession #Q9EP73) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions.
  • Specification
  • Gene Information
  • Related Products
Source : Human cells
Species : Mouse
Tag : Fc
Form : Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule).
Bio-activity : Binds to its receptor PD-1 and anti-PD-L1 monoclonal antibody. Blocks PD-L1"s binding to its receptor and mediated signaling activity. Shows cross-species binding to human PD-1 and human CD80 in a functional ELISA
Molecular Mass : Calculated molecular mass 51.5 kDa; estimated by SDS-PAGE under reducing condition 60-65 kDa suggesting that the protein is highly glycosylated
Endotoxin : <0.1 eu per 1 μg of purified recombinant protein determined by the lal>
Purity : >95% judged by SDS-PAGE under reducing condition
Storage : The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
Gene Name : Cd274 CD274 antigen [ Mus musculus ]
Official Symbol : Cd274
Synonyms : CD274; CD274 antigen; programmed cell death 1 ligand 1; B7 homolog 1; PDCD1 ligand 1; programmed death ligand 1; B7h1; Pdl1; Pdcd1l1; Pdcd1lg1; A530045L16Rik;
Gene ID : 60533
mRNA Refseq : NM_021893
Protein Refseq : NP_068693
MIM :
UniProt ID :
Pathway : Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem;
Function : protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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