Recombinant Human PRKCD protein, His-tagged

• Cat.No.: PRKCD-357H
• Product Overview: Recombinant Human PRKCD(Met1-Asp676) fussed with His tag at C-terminal was expressed in HEK293.

Specification

• Description: Protein Kinase C Delta Type (PRKCD) is a member of the AGC Ser/Thr protein kinase family of protein kinase superfamily. PKC family members phosphorylate a variety of protein targets and are known to be involved in diverse cellular signaling pathways. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PRKCD serves as a major receptor for phorbol esters, a class of tumor promoters. PRKCD is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types.
• Source: HEK293
• Species: Human
• Tag: His
• AA Sequence: MAPFLRIAFNSYELGSLQAEDEANQ PFCAVKMKEALSTERGKTLVQKKPT MYPEWKSTFD AHIY EGRVIQIVLMRAAEEPVSEVTVGVS VLAERCKKNNGKAEFWLDLQPQAKV LMSVQY FLEDVDCK QSMRSEDEAKFPTMNRRGAIKQAKI HYIKNHEFIATFFGQPTFCSVCKDF VW GLNKQGYKCRQC NAAIHKKCIDKIIGRCTGTAANSRD TIFQKERFNIDMPHRFKVHNYMS PTFCDHCGSLLWGLVK QGLKCEDCGMNVHHKCREKVANLCG INQKLLAEALNQVTQRASR RSDSASSEPVGIYQGFEKKT GVAGEDMQDNSGTYGKIWEGSSKCN INNFIFHKVLGKGSF GKVLLGELKGRGEYFAIKALKKDV VLIDDDVECTMVEKRVLTLAAENPF LTHLICTFQTK DHLFFVMEFLNGGDLMYHIQDKGRF ELY RATFYAAEIMCGLQFLHSKGIIYRD LKLDNVL LDRDGHIKIADFGMCKENIFGESRA STFCGTP DYIAPEILQGLKYTFSVDWWSFGVL LYE MLIGQSPFHGDDEDELFESIRVDTP HYPRWITKESK DILEKLFEREPTKRLGVTGNIKIH PFFKTINWTLLEKRRLEPPFRPKVK SPRDYSNFDQEFLNE KARLSYSDKNLIDSMDQSAF AGFSFVNPKFEHLLEDLDHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at < -20 centigrade, stable for 6 months after receipt.Please minimize freeze-thaw cycles.

Gene Information

• Gene Name: PRKCD protein kinase C, delta [ Homo sapiens ]
• Official Symbol: PRKCD
• Synonyms: PRKCD; protein kinase C, delta; protein kinase C delta type; protein kinase C delta VIII; tyrosine-protein kinase PRKCD; MAY1; PKCD; nPKC-delta; MGC49908
• Gene ID: 5580
• mRNA Refseq: NM_006254
• Protein Refseq: NP_006245
• MIM: 176977
• UniProt ID: Q05655
• Chromosome Location: 3p21.31
• Pathway: Alpha-synuclein signaling, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Ca-dependent events, organism-specific biosystem
• Function: ATP binding; calcium-independent protein kinase C activity; enzyme activator activity; enzyme binding; insulin receptor substrate binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein C-terminus binding; protein binding; protein kinase activity; protein serine/threonine kinase activity