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Recombinant Human GNAL protein, GST-tagged

Cat.No. : GNAL-45H
Product Overview : Recombinant Human GNAL(1 a.a. - 458 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
  • Specification
  • Gene Information
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Description : This gene encodes a stimulatory G protein alpha subunit which mediates odorant signaling in the olfactory epithelium. This protein couples dopamine type 1 receptors and adenosine A2A receptors and is widely expressed in the central nervous system. Mutations in this gene have been associated with dystonia 25 and this gene is located in a susceptibility region for bipolar disorder and schizophrenia. Alternative splicing results in multiple transcript variants.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 78.9 kDa
AA Sequence : MGLCYSLRPLLFGGPGDDPCAASEP PVEDAQPAPAPALAPVRAAARDTAR TLLPRGGEGSPACARPKADKPKEKR QRTEQLSAEEREAAKEREAVKEARK VSRGIDRMLRDQKRDLQQTHRLLLL GAGESGKSTIVKQMRILHVNGFNPE EKKQKILDIRKNVKDAIVTIVSAMS TIIPPVPLANPENQFRSDYIKSIAP ITDFEYSQEFFDHVKKLWDDEGVKA CFERSNEYQLIDCAQYFLERIDSVS LVDYTPTDQDLLRCRVLTSGIFETR FQVDKVNFHMFDVGGQRDERRKWIQ CFNDVTAIIYVAACSSYNMVIREDN NTNRLRESLDLFESIWNNRWLRTIS IILFLNKQDMLAEKVLAGKSKIEDY FPEYANYTVPEDATPDAGEDPKVTR AKFFIRDLFLRISTATGDGKHYCYP HFTCAVDTENIRRVFNDCRDIIQRM HLKQYELL
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type [ Homo sapiens ]
Official Symbol : GNAL
Synonyms : GNAL; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; guanine nucleotide-binding protein G(olf) subunit alpha; adenylate cyclase-stimulating G alpha protein, olfactory type; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory typ; guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide, olfactory type;
Gene ID : 2774
mRNA Refseq : NM_182978
Protein Refseq : NP_892023
MIM : 139312
UniProt ID : P38405
Chromosome Location : 18p11.22-p11.21
Pathway : Activation of GABAB receptors, organism-specific biosystem; Adenylate cyclase activating pathway, organism-specific biosystem; Adenylate cyclase inhibitory pathway, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem;
Function : G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; GTP binding; GTPase activity; adenylate cyclase activity; guanyl nucleotide binding; metal ion binding; nucleotide binding; signal transducer activity; signal transducer activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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