Recombinant Human DPP4 protein, His-tagged

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Recombinant Human DPP4 protein, His-tagged

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Cat.No. : DPP4-215H
Product Overview : Recombinant Human DPP4(39 a.a. - 766 a.a.) fused with His tag was expressed in E. coli.
Description : The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides.
Source : E. coli
Species : Human
Tag : His
Form : In 20 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, pH 8.0 (10% glycerol)
Bio-activity : Approximately > 50 Unit/mg.
Molecular Mass : 86.4 kDa
AA Sequence : ADPRKTYTLT DYLKNTYRLK LYSLRWISDH EYLYKQENNI LVFNAEYGNS SVFLENSTFD EFGHSINDYS ISPDGQFILL EYNYVKQWRH SYTASYDIYD LNKRQLITEE RIPNNTQWVT WSPVGHKLAY VWNNDIYVKI EPNLPSYRIT WTGKEDIIYN GITDWVYEEE VFSAYSALWW SPNGTFLAYA QFNDTEVPLI EYSFYSDESL QYPKTVRVPY PKAGAVNPTV KFFVVNTDSL SSVTNATSIQ ITAPASMLIG DHYLCDVTWA TQERISLQWL RRIQNYSVMD ICDYDESSGR WNCLVARQHI EMSTTGWVGR FRPSEPHFTL DGNSFYKIIS NEEGYRHICY FQIDKKDCTF ITKGTWEVIG IEALTSDYLY YISNEYKGMP GGRNLYKIQL SDYTKVTCLS CELNPERCQY YSVSFSKEAK YYQLRCSGPG LPLYTLHSSV NDKGLRVLED NSALDKMLQN VQMPSKKLDF IILNETKFWY QMILPPHFDK SKKYPLLLDV YAGPCSQKAD TVFRLNWATY LASTENIIVA SFDGRGSGYQ GDKIMHAINR RLGTFEVEDQ IEAARQFSKM GFVDNKRIAI WGWSYGGYVT SMVLGSGSGV FKCGIAVAPV SRWEYYDSVY TERYMGLPTP EDNLDHYRNS TVMSRAENFK QVEYLLIHGT ADDNVHFQQS AQISKALVDV GVDFQAMWYT DEDHGIASST AHQHIYTHMS HFIKQCFSLP -SGRLVPRGS HHHHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : > 95% by SDS-PAGE
Unit Definition : One unit will hydrolyze 1 umole of p-nitroaniline per minute at pH 8.0 at 37 centigrade using 1mM of Gly-Pro p-nitroanilde as a substrate.
Applications : Functional Study; SDS-PAGE
Storage : Store at 4 centigrade for 1-2 weeks. For long term storage store at -20 centigrade or -80 centigrade.Aliquot to avoid repeated freezing and thawing.
Concentration : 0.5 mg/mL
Gene Name : DPP4 dipeptidyl-peptidase 4 [ Homo sapiens ]
Official Symbol : DPP4
Synonyms : DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103;
Gene ID : 1803
mRNA Refseq : NM_001935
Protein Refseq : NP_001926
MIM : 102720
UniProt ID : P27487
Chromosome Location : 2q23-qter
Pathway : Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1), organism-specific biosystem;
Function : aminopeptidase activity; collagen binding; dipeptidyl-peptidase activity; peptidase activity; peptide binding; protease binding; protein binding; protein homodimerization activity; receptor activity; receptor binding; serine-type endopeptidase activity; serine-type peptidase activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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