"Tnfrsf18" Related Products

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Recombinant Mouse Tnfrsf18 protein, His-tagged

Cat.No.: Tnfrsf18-15M
Product Overview: Recombinant Mouse Tnfrsf18(Ser 22 - His 153) fused with His tag at C-terminal was expressed in HEK293.
Description: Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Source: HEK293
Species: Mouse
Tag: His
Predicted N Terminal: Ser 22
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Molecular Mass: Has a calculated MW of 15.2 kDa. DTT-reduced Protein migrates as 27-34 kDa in SDS-PAGE.
Endotoxin: Less than 1.0 EU per μg of the protein by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles.No activity loss was observed after storage at:In lyophilized state for 1 year (4 centigrade); After reconstitution under sterile conditions for 3 months (-70 centigrade).
Gene Name: Tnfrsf18 tumor necrosis factor receptor superfamily, member 18 [ Mus musculus ]
Official Symbol: Tnfrsf18
Synonyms: TNFRSF18; tumor necrosis factor receptor superfamily, member 18; tumor necrosis factor receptor superfamily member 18; glucocorticoid-induced TNFR-related protein; AITR; Gitr;
Gene ID: 21936
mRNA Refseq: NM_009400
Protein Refseq: NP_033426
MIM:
UniProt ID: O35714
Chromosome Location: 4; 4 E
Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function: binding; protein binding; receptor activity;

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