Recombinant Human ANGPTL3 protein, His-tagged ANGPTL3-32H

Recombinant Human ANGPTL3 protein, His-tagged

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Recombinant Human ANGPTL3 protein, His-tagged

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Cat.No. : ANGPTL3-32H
Product Overview : Recombinant human ANGPTL3, fused to His-tag at N-terminus, was expressed in E.coli.
Description : ANGPTL3 also known as Angiopoietin-related protein 3 is a member of the angiopoietin-like family of secreted factors. It is expressed predominantly in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain, and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl (pH8.0) containing 10% glycerol
Molecular Mass : 27.7kDa (239aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MPAECTTIYN RGEHTSGMYA IRPSNSQVFH VYCDVISGSP WTLIQHRIDG SQNFNETWEN YKYGFGRLDG EFWLGLEKIY SIVKQSNYVL RIELEDWKDN KHYIEYSFYL GNHETNYTLH LVAITGNVPN AIPENKDLVF STWDHKAKGH FNCPEGYSGG WWWHDECGEN NLNGKYNKPR AKSKPERRRG LSWKSQNGRL YSIKSTKMLI HPTDSESFE
Purity : >90% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1mg/ml (determined by Bradford assay)
Gene Name : ANGPTL3 angiopoietin-like 3 [ Homo sapiens ]
Official Symbol : ANGPTL3
Synonyms : ANGPTL3; angiopoietin-like 3; ANGPT5; angiopoietin-related protein 3; angiopoietin 5; ANG-5; FHBL2;
Gene ID : 27329
mRNA Refseq : NM_014495
Protein Refseq : NP_055310
MIM : 604774
UniProt ID : Q9Y5C1
Chromosome Location : 1p31.1-p22.3
Pathway : Integrins in angiogenesis, organism-specific biosystem;
Function : cell surface binding; enzyme inhibitor activity; growth factor activity; integrin binding; phospholipase inhibitor activity;

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