Recombinant Human ACP5 protein, His-tagged

• Cat.No.: ACP5-38H
• Product Overview: Recombinant human ACP5, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: ACP5, also known as tartrate-resistant acid phosphatase type 5, is involved in osteopontin and bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 35.1kDa (310aa) 28-40kDa (SDS-PAGE under reducing conditions)
• AA Sequence: ATPALRFVAV GDWGGVPNAP FHTAREMANA KEIARTVQIL GADFILSLGD NFYFTGVQDI NDKRFQETFE DVFSDRSLRK VPWYVLAGNHDHLGNVSAQI AYSKISKRWN FPSPFYRLHF KIPQTNVSVA IFMLDTVTLC GNSDDFLSQQ PERPRDVKLA RTQLSWLKKQ LAAAREDYVLVAGHYPVWSI AEHGPTHCLV KQLRPLLATY GVTAYLCGHD HNLQYLQDEN GVGYVLSGAG NFMDPSKRHQ RKVPNGYLRF HYGTEDSLGGFAYVEISSKE MTVTYIEASG KSLFKTRLPR RARPHHHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >95% by SDS – PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: ACP5 acid phosphatase 5, tartrate resistant [ Homo sapiens ]
• Official Symbol: ACP5
• Synonyms: ACP5; acid phosphatase 5, tartrate resistant; tartrate-resistant acid phosphatase type 5; tartrate resistant acid phosphatase; TRAP; TrATPase; tartrate-resistant acid ATPase; SPENCDI
• Gene ID: 54
• mRNA Refseq: NM_001111034
• Protein Refseq: NP_001104504
• MIM: 171640
• UniProt ID: P13686
• Chromosome Location: 19p13.3-p13.2
• Pathway: Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Osteoclast Signaling, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem
• Function: acid phosphatase activity; ferric iron binding; ferrous iron binding; hydrolase activity; metal ion binding