"PPP2R1A" Related Products

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Recombinant Human PPP2R1A protein, His-tagged

Cat.No.: PPP2R1A-43H
Product Overview: Recombinant human PPP2R1A, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: PPP2R1A also known as Serine/Threonine-Protein Phosphatase 2A 65 kDa regulatory subunit A alpha isoform, is a member of the PPP family of phosphatases, regulates a variety of essential cellular processes. PPP2R1A phosphorylation is an in vivo mechanism for regulation of the PP2A signaling complex and increased PP2A activity in heart failure.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In Phosphate Buffered Saline (pH7.4) containing 10% glycerol
Molecular Mass: 67.7kDa (612aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAAADGD DSLYPIAVLI DELRNEDVQL RLNSIKKLST IALALGVERT RSELLPFLTD TIYDEDEVLLALAEQLGTFT TLVGGPEYVH CLLPPLESLA TVEETVVRDK AVESLRAISH EHSPSDLEAH FVPLVKRLAG GDWFTSRTSA CGLFSVCYPRVSSAVKAELR QYFRNLCSDD TPMVRRAAAS KLGEFAKVLE LDNVKSEIIP MFSNLASDEQ DSVRLLAVEA CVNIAQLLPQ EDLEALVMPTLRQAAEDKSW RVRYMVADKF TELQKAVGPE ITKTDLVPAF QNLMKDCEAE VRAAASHKVK EFCENLSADC RENVIMSQIL PCIKELVSDANQHVKSALAS VIMGLSPILG KDNTIEHLLP LFLAQLKDEC PEVRLNIISN LDCVNEVIGI RQLSQSLLPA IVELAEDAKW RVRLAIIEYMPLLAGQLGVE FFDEKLNSLC MAWLVDHVYA IREAATSNLK KLVEKFGKEW AHATIIPKVL AMSGDPNYLH RMTTLFCINV LSEVCGQDITTKHMLPTVLR MAGDPVANVR FNVAKSLQKI GPILDNSTLQ SEVKPILEKL TQDQDVDVKY FAQEALTVLS LA
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Absorbance at 280nm)
Gene Name: PPP2R1A protein phosphatase 2, regulatory subunit A, alpha [ Homo sapiens ]
Official Symbol: PPP2R1A
Synonyms: PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform , protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; PP2A Aalpha; PR65A; protein phosphatase 2; 65kDa regulatory subunit A; protein phosphatase 2A; regulatory subunit A; alpha isoform; PP2A subunit A isoform R1-alpha; PP2A subunit A isoform PR65-alpha; medium tumor antigen-associated 61 KDA protein; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform; PP2AAALPHA; MGC786; PP2A-Aalpha;
Gene ID: 5518
mRNA Refseq: NM_014225
Protein Refseq: NP_055040
MIM: 605983
UniProt ID: P30153
Chromosome Location: 19q13
Pathway: Activated TLR4 signalling, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Beta-catenin phosphorylation cascade, organism-specific biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem;
Function: antigen binding; protein binding; protein heterodimerization activity; protein phosphatase type 2A regulator activity; protein serine/threonine phosphatase activity;

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