|Cat. No. :
|Product Overview :
||RecombinantHuman Activin-A also called Activin-Beta A chain inE.Coliis a single monomeric, non-glycosylated, polypeptide chain containing 116 amino acids fragment (311-426) and having an amino-terminal hexa-histidine tag, having a total molecular weight of 17.47 kDa. The Inhibin-Beta A chain is purified by standard chromatographic techniques.
||Inhibins are dimeric peptide hormones produced by female ovarian granulose cells and male Sertoli cells as well as a variety of other tissues. Inhibins have two isoforms, A and B, with the same alpha subunit but different beta subunits. Inhibin A is a dimer of alpha and beta A subunits, inhibin B is a dimer of alpha and beta B subunits. Inhibins are thought to inhibit the production of follicle-stimulating hormone (FSH) by the pituitary gland. In addition, Inhibins are also thought to play a role in the control of gametogenesis, and embryonic and fetal development.
|Physical Appearance :
||Sterile Filtered clear solution (0.185 mg/ml).
||Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
||Activin-A is supplied in 20 mM Tris pH-8 and 50% glycerol.
||Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.