"PARK7" Related Products

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Recombinant Human PARK7, His-tagged

Cat. No. : PARK7-114H
Product Overview : Recombinant Human Parkinson disease (autosomal recessive, early onset) 7 (His-Tagged) produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 225 amino acids and has a molecular mass of 24 kDa.
Description : The DJ-1 is a ubiquitously expressed protein involved in various cellular processes including spermatogenesis and fertilization, cancer, RNA-binding, androgen-receptor signaling and oxidative stress. Mutations in the DJ-1 are the cause of autosomal recessive early-onset Parkinson's disease 7 (Park7).
Source : Escherichia Coli.
Amino Acid Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASK RALVILAKGA EEMETVIPVD VMRRAGIKVT VAGLAGKDPV QCSRDVVICP DASLEDAKKE GPYDVVVLPG GNLGAQNLSE SAAVKEILKE QENRKGLIAA ICAGPTALLA HEIGFGSKVT THPLAKDKMM NGGHYTYSEN RVEKDGLILT SRGPGTSFEF ALAIVEALNG KEVAAQVKAP LVLKD.
Physical Appearance : Sterile Filtered colorless solution.
Formulation : The protein solution (1mg/ml) cotains 20mM Tris-HCl Ph-8 and 20% glycerol.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Stability : DJ-1 although stable 14°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
PDB rendering based on 1j42. :

Gene Name : PARK7 Parkinson disease (autosomal recessive, early onset) 7 [ Homo sapiens ]
Synonyms : PARK7; Parkinson disease (autosomal recessive, early onset) 7; DJ1; DJ-1; FLJ27376; FLJ34360; FLJ92274; Parkinson disease protein 7; oncogene DJ1; oncogene DJ1; protein DJ-1; OTTHUMP00000001350; OTTHUMP00000001351; OTTHUMP00000001348; OTTHUMP00000001349
Gene ID : 11315
mRNA Refseq : NM_001123377
Protein Refseq : NP_001116849
UniProt ID : Q99497
Chromosome Location : 1p36
MIM : 602533
Pathway : Parkinson"s disease
Function : peroxiredoxin activity; protein binding

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