Recombinant Human Retinoid X Receptor, Alpha
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat. No. : | RXRA -199H |
Product Overview : | The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques (119 aa, 13.6 kDa). |
Description : | The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR a, b, g . Human RXR a gene is localized on 9q34.9 and encodes two major isoforms(RXR a1, RXR a2). |
Source : | Escherichia Coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl, 5 mM b-Mercaptoethanol. |
Molecular Weight : | 13.6 kDa (119 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Amino acid Sequence : | MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
PDBrendering based on 1by4. Available structures:1by4, 1dkf, 1dsz, 1fby, 1fm6, 1fm9, 1g1u, 1g5y, 1k74, 1lbd, 1mv9, 1mvc, 1mzn, 1r0n, 1rdt, 1rxr, 1xdk, 1xls, 1xv9, 1xvp, 1ynw, 2acl, 2nll. : |
![]() |
Gene Name : | RXRA retinoid X receptor, alpha [ Homo sapiens ] |
Synonyms : | RXRA; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720; NR2B1; OTTHUMP00000022510; Retinoid X receptor alpha; retinoid X receptor, alpha; Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor, alpha; Retinoid X receptor alpha (RXR-alpha). |
Gene ID : | 6256 |
mRNA Refseq : | NM_002957 |
Protein Refseq : | NP_002948 |
MIM : | 180245 |
UniProt ID : | P19793 |
Chromosome Location : | 9q34.3 |
Pathway : | Adipocytokine signaling pathway; Non-small cell lung cancer; PPAR signaling pathway; Small cell lung cancer; Thyroid cancer. |
Function : | ligand-regulated transcription factor activity; metal ion binding; protein binding; retinoid-X receptor activity; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor activity; vitamin D receptor binding; vitamin D response element binding; zinc ion binding. |
◆ Recombinant Protein
RXRA-2013H | Recombinant Human RXRA Protein, MYC/DDK-tagged | +Inquiry |
RXRA-5479H | Recombinant Human Retinoid X Receptor, Alpha, His-tagged | +Inquiry |
Rxra-5659M | Recombinant Mouse Rxra Protein, Myc/DDK-tagged | +Inquiry |
RXRA-31121TH | Recombinant Human RXRA, His-tagged | +Inquiry |
RXRA-31120TH | Recombinant Human RXRA, His-tagged | +Inquiry |
|
◆ Lysates
RXRA-1554HCL | Recombinant Human RXRA cell lysate | +Inquiry |
|
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy