Recombinant Human Retinoid X Receptor, Alpha
Cat.No. : | RXRA-199H |
Product Overview : | The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques (119 aa, 13.6 kDa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | RXRA -199H |
Description : | The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR a, b, g . Human RXR a gene is localized on 9q34.9 and encodes two major isoforms(RXR a1, RXR a2). |
Source : | Escherichia Coli. |
Formulation : | Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl, 5 mM b-Mercaptoethanol. |
Molecular Weight : | 13.6 kDa (119 aa). |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Amino acid Sequence : | MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | RXRA retinoid X receptor, alpha [ Homo sapiens ] |
Synonyms : | RXRA; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720; NR2B1; OTTHUMP00000022510; Retinoid X receptor alpha; retinoid X receptor, alpha; Nuclear receptor subfamily 2 group B member 1; Retinoid X receptor, alpha; Retinoid X receptor alpha (RXR-alpha). |
Gene ID : | 6256 |
mRNA Refseq : | NM_002957 |
Protein Refseq : | NP_002948 |
MIM : | 180245 |
UniProt ID : | P19793 |
Chromosome Location : | 9q34.3 |
Pathway : | Adipocytokine signaling pathway; Non-small cell lung cancer; PPAR signaling pathway; Small cell lung cancer; Thyroid cancer. |
Function : | ligand-regulated transcription factor activity; metal ion binding; protein binding; retinoid-X receptor activity; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor activity; vitamin D receptor binding; vitamin D response element binding; zinc ion binding. |
Products Types
◆ Recombinant Protein | ||
RXRA-5479H | Recombinant Human Retinoid X Receptor, Alpha, His-tagged | +Inquiry |
Rxra-5659M | Recombinant Mouse Rxra Protein, Myc/DDK-tagged | +Inquiry |
RXRA-1931H | Recombinant Human RXRA Protein, His (Fc)-Avi-tagged | +Inquiry |
RXRA-2668H | Recombinant Human RXRA Protein, His-tagged | +Inquiry |
RXRA-2013H | Recombinant Human RXRA Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
RXRA-1554HCL | Recombinant Human RXRA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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