"YWHAG" Related Products

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Recombinant Human YWHAG

Cat. No. : YWHAG-12H
Product Overview : Recombinant Human KCIP-1 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 247 amino acids (1-247) and having a molecular mass of 28 kDa. 14-3-3-gamma is purified by proprietary chromatographic techniques.
Description : The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Source : Escherichia Coli.
Amino Acid Sequence : MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD DGGEGNN.
Physical Appearance : Sterile filtered colorless solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : 1 mg/ml solution containing 20mM Tris 7.5.
Storage : Recombinant Human 14-3-3 Gamma although stable at 14°Cfor 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Gene Name : YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [ Homo sapiens ]
Synonyms : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3GAMMA; YWHAG; 14-3-3 gamma; KCIP-1; Protein kinase C inhibitor protein 1
Gene ID : 7532
mRNA Refseq : NM_012479
Protein Refseq : NP_036611
MIM : 605356
UniProt ID : P61981
Chromosome Location : 7q11.23
Pathway : Cell cycle; Cell Cycle, Mitotic; Neurotrophin signaling pathway
Function : insulin-like growth factor receptor binding; protein kinase C inhibitor activity; protein domain specific binding; protein kinase C binding

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