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Recombinant Human YWHAG

Cat.No. : YWHAG-12H
Product Overview : Recombinant Human KCIP-1 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing 247 amino acids (1-247) and having a molecular mass of 28 kDa. 14-3-3-gamma is purified by proprietary chromatographic techniques.
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Cat. No. : YWHAG-12H
Description : The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3gamma, a subtype of the 14-3-3 family of proteins, was thought to be brain and neuron-specific. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Source : Escherichia Coli.
Amino Acid Sequence : MVDREQLVQK ARLAEQAERY DDMAAAMKNV TELNEPLSNE ERNLLSVAYK NVVGARRSSW RVISSIEQKT SADGNEKKIE MVRAYREKIE KELEAVCQDV LSLLDNYLIK NCSETQYESK VFYLKMKGDY YRYLAEVATG EKRATVVESS EKAYSEAHEI SKEHMQPTHP IRLGLALNYS VFYYEIQNAP EQACHLAKTA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDD DGGEGNN.
Physical Appearance : Sterile filtered colorless solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : 1 mg/ml solution containing 20mM Tris 7.5.
Storage : Recombinant Human 14-3-3 Gamma although stable at 14°Cfor 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Gene Name : YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide [ Homo sapiens ]
Synonyms : tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; 14-3-3GAMMA; YWHAG; 14-3-3 gamma; KCIP-1; Protein kinase C inhibitor protein 1
Gene ID : 7532
mRNA Refseq : NM_012479
Protein Refseq : NP_036611
MIM : 605356
UniProt ID : P61981
Chromosome Location : 7q11.23
Pathway : Cell cycle; Cell Cycle, Mitotic; Neurotrophin signaling pathway
Function : insulin-like growth factor receptor binding; protein kinase C inhibitor activity; protein domain specific binding; protein kinase C binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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