"NKX2-1" Related Products

Recombinant Human NK2 Homeobox 1

Cat. No.: NKX2-1-226H
Product Overview: Recombinant human TTF-1 protein expressed inE.coliencodes138-286 amino acids and has a molecular mass of 41 kDa.
Description: TTF-1 (Thyroid transcription factor-1) is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. TTF-1 is detected in primary lung adenocarcinomas and small cell carcinomas and is absent in colon and breast carcinomas. Staining with TTF-1 antibody is useful for distinguishing between tumors of lung and non-lung origin.
Source: Recombinant human TTF-1 protein encoding 138-286 amino acids expressed inE.coli.
Formulation: 100µl purified human TTF-1 protein at 0.1mg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Application And Suggested Dilutions: •ELISA •Inhibition Assays •Western Blotting
Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 41 kDa.
Activity: Not known.
Storage & Stability: Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
Gene Name: NKX2-1 NK2 homeobox 1 [ Homo sapiens ]
Synonyms: NKX2-1; NK2 homeobox 1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; TITF1; TTF-1; NKX2.1;thyroid transcription factor 1; NK-2 homolog A; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; thyroid nuclear factor; benign chorea
Gene ID: 7080
mRNA Refseq: NM_001079668
Protein Refseq: NP_001073136
MIM: 600635
UniProt ID: P43699
Chromosome Location: 14q13
Function: RNA polymerase II transcription factor activity, enhancer binding; promoter binding; protein binding; specific RNA polymerase II transcription factor activity; transcription activator activity

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