Recombinant Human AP3S2, T7-tagged

• Cat.No.: AP3S2-71H
• Product Overview: Recombinant Human adaptor-related protein complex 3, sigma 2 subunit produced inE.coliis a non-glycosylated, polypeptide chain containing amino acids (1-193) and having a total molecular mass of 22.2 kDa. rhAP3S2 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.

Specification

• Cat. No.: AP3S2-71H
• Description: Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.
• Source: Escherichia coli.
• Physical Appearance: Sterile Filtered clear solution.
• Purity: Greater than 95.0% as determined by the analysis by reducing and non-reducing SDS-PAGE coomassie blue staining.
• Formulation: Recombinant Human AP2M1 at a concentration of 0.1mg/ml containing 10 mM Tris, pH 8.0, 0.01% Triton X-100 and 0.002% NaN3 and 10mM DTT.
• Applications: • ELISA • MS• Western Blotting.
• Storage: RhAP3S2 although stable at 14°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: AP3S2 adaptor-related protein complex 3, sigma 2 subunit [ Homo sapiens ]
• Synonyms: AP3S2; adaptor-related protein complex 3, sigma 2 subunit; AP3S3; sigma3b; FLJ35955; AP-3 complex subunit sigma-2; Adapter-related protein complex 3 sigma-2 subunit; AP-3 complex sigma-3B subunit; Sigma-adaptin 3b; Sigma3B-adaptin; clathrin-associated/assembly/adaptor protein, small 4, 22-kD; adaptor complex sigma3B
• Gene ID: 10239
• mRNA Refseq: NM_005829
• Protein Refseq: NP_005820
• MIM: 602416
• UniProt ID: P59780
• Chromosome Location: 15q26.1
• Pathway: Lysosome
• Function: protein binding; protein transporter activity