Recombinant Human Collapsin Response Mediator Protein 1 CRMP1-110H

Recombinant Human Collapsin Response Mediator Protein 1

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Recombinant Human Collapsin Response Mediator Protein 1

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Cat. No. : CRMP1-110H
Product Overview : Recombinant Human Collapsin Response Mediator Protein 1 protein expressed inE.coliencodes 448-568 amino acids and has a molecular mass of 39 kDa.
Description : Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The X-ray crystal structure of murine CRMP1 was determined at 2.1 resolution and demonstrates that CRMP1 is a bilobed 'lung-shaped' protein forming a tetrameric assembly.
Source : Escherichia Coli.
Formulation : Recombinant Human CRMP-1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
Application And Suggested Dilutions : •ELISA •Inhibition Assays •Western Blotting.
Characterization : On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 39 kDa.
Storage & Stability : Store vial at -200°Cto -800°C. When stored at the recommended temperature, this protein is stable for 12 months.
PDB rendering based on 1kcx. :

Gene Name : CRMP1 collapsin response mediator protein 1 [ Homo sapiens ]
Synonyms : CRMP1; collapsin response mediator protein 1; DRP1; DRP-1; DPYSL1; Dihydropyrimidinase-related protein 1;CRMP-1; dihydropyrimidinase related protein-1; dihydropyrimidinase-like 1
Gene ID : 1400
mRNA Refseq : NM_001014809
Protein Refseq : NP_001014809
UniProt ID : Q14194
Chromosome Location : 4p16.1
MIM : 602462
Pathway : Axon guidance
Function : dihydropyrimidinase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding

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