Recombinant Human KIR2DL4

• Cat.No.: KIR2DL4-147H
• Product Overview: Recombinant KIR2DS4 protein produced inE.Coliis a single, non-glycosylated polypeptide chain. The protein contains 202 amino acids and has a molecular mass of 22.2 kDa.

Specification

• Cat. No.: KIR2DL4-147H
• Description: KIR2DS4 protein is an activating Killer Cell Ig-like Receptor (KIR, previously called p50 KIR, p50.3, cl39, or KAR-K1), which may recognize class I MHC molecules.
• Source: Escherichia Coli.
• Amino Acid Sequence: MEGVHRKPSF LALPGHLVKS EETVILQCWS DVMFEHFLLH REGKFNNTLH LIGEHHDGVS KANFSIGPMM PVLAGTYRCY GSVPHSPYQL SAPSDPLDMV IIGLYEKPSL SAQPGPTVQA GENVTLSCSS RSSYDMYHLS REGEAHERRL PAVRSINGTF QADFPLGPAT HGGTYRCFGS FRDAPYEWSN SSDPLLVSVT GN.
• Physical Appearance: Sterile filtered clorless solution.
• Formulation: The protein (1mg/ml) contains 20mM Tris-HCl (pH7.5).
• Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by reducing and non-reducing SDS-PAGE Coomassie.
• Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Gene Information

• Gene Name: KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 [ Homo sapiens ]
• Synonyms: killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; G9P; CD158D; KIR103; KIR103AS; KIR2DL4; NK cell receptor;natural killer cell inhibitory receptor; 103AS; 15.212; KIR-103AS; OTTHUMP00000068610; CD158 antigen-like family member D; CD158d antigen; Killer cell inhibitory receptor 103AS; MHC class I NK cell receptor KIR103AS
• Gene ID: 3805
• mRNA Refseq: NM_001080770
• Protein Refseq: NP_001074239
• MIM: 604945
• UniProt ID: Q99706
• Pathway: Antigen processing and presentation; Natural killer cell mediated cytotoxicity; Signaling in Immune system
• Function: transmembrane receptor activity