||Recombinant Human Lymphatic Vessel Endothelial Hyluronan Receptor-1 protein expressed inE.coliencodes amino acids 243-323 and has a molecular mass of 36 kDa.
||The pace of research into the lymphatic system continues to accelerate with the availability of new molecular markers. One such marker, LYVE-1, the lymphatic receptor for the extracellular matrix mucopolysaccharide hyaluronan, has been a key component of many important studies on embryonic and tumour-induced lymphangiogenesis, and continues to be used for the detection and isolation of lymphatic endothelial cells. However, LYVE-1 is interesting in its own right. Being a member of the Link protein family whose only other major hyaluronan receptor is directly involved in leukocyte migration and tumor metastasis, LYVE-1 is already implicated in the trafficking of cells within lymphatic vessels and lymph nodes. The current challenge is to determine the precise roles played by LYVE-1 and other scavenger type receptors in the immune functions of the lymphatics as well as to use LYVE-1 and other markers to investigate the way in which tumours exploit lymphatic vessels for metastasis.
||Recombinant Human LYVE-1 protein encoding 243-323 a.a expressed inE.coli.
||Recombinant Human LYVE-1 protein at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
|Application And Suggested Dilutions:
||•ELISA •Inhibition Assays •Western Blotting.
||On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 36kDa.
|Storage & Stability:
||Store vial at -20°Cto -80°C. When stored at the recommended temperature, this protein is stable for 12 months.