||Recombinant Human microseminoprotein, beta-(His-tagged) produced inE.Coliis a single, non-glycosylated, polypeptide chain. The Human IGBF contains 104 amino acids and has a molecular mass of 12 kDa. The Human IGBF is purified by proprietary chromatographic techniques.
||Microseminoprotein is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene.
|Amino Acid Sequence:
||MKHHHHHHAS SCYFIPNEGV PGDSTRKCMD LKGNKHPINS EWQTDNCETC TCYETEISCC TLVSTPVGYD KDNCQRIFKK EDCKYIVVEK KDPKKTCSVS EWII.
||Sterile Filtered White lyophilized (freeze-dried) powder.
||The sterile filtered concentrated (0.5mg/ml) protein solution was lyophilized with 20mM Tris & 20mM NaCl pH-7.5.
||Add deionized water to a working concentration of 0.5mg/ml and let the lyophilized pellet dissolve completely.
||Greater than 95% as determined by SDS-PAGE.
||Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time.