||Recombinant Human S100 Calcium Binding Protein A2 cloned from human cDNA, and expressed inE.coli. The protein consists of the human S100A2 (residues 1-98 swissprot accession P29034). MW = 11.7 kDa.
||The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
||> 95% by SDS-PAGE. The protein was observed as a single band migrating at a molecular weight <14 kDa).
||1mg at 1mg/ml in 50mM Tris, 2mM DTT pH 6.5. The concentration is calculated from the absorbance at 280nm (e280 = 3230 M-1 cm-1).
||Under the above described conditions, to avoid precipitation or aggregation, the product can be concentrated to a maximum of 1mM.
||-20º C. The protein is stable at 25 ºC for at least several hours. After initial defrost, aliquot product into individual tubes and refreeze at -20º C. Avoid repeated freeze/defrost cycles.