Recombinant Human Bone Morphogenetic Protein 5

• Cat.No.: BMP5-11H
• Product Overview: Recombinant BMP5 was expressed inE.coliand purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. MW = 15.7 kDa (139aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: BMP5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMP5 may play a role in certaincancers. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis.
• Amino Acid Sequence: MAANKRKNQN RNKSSSHQDS SRMSSVGDYN TSEQKQACKK HELYVSFRDL GWQDWIIAPE GYAAFYCDGE CSFPLNAHMN ATNHAIVQTL VHLMFPDHVP KPCCAPTKLN AISVLYFDDS SNVILKKYRN MVVRSCGCH
• Form: Liquid. In 10mM Sodium Citrate buffer (pH3.5) containing 10% Glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method ).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: BMP5 bone morphogenetic protein 5 [ Homo sapiens ]
• Synonyms: BMP5; bone morphogenetic protein 5; MGC34244; BMP-5; OTTHUMP00000016650
• Gene ID: 653
• mRNA Refseq: NM_021073
• Protein Refseq: NP_066551
• MIM: 112265
• UniProt ID: P22003
• Chromosome Location: 6p12.1
• Pathway: Cytokine-cytokine receptor interaction; Hedgehog signaling pathway; TGF-beta signaling pathway
• Function: cytokine activity; growth factor activity; IEA protein binding