Recombinant Human Interleukin 4, His-tagged
Cat.No. : | IL4-137H |
Product Overview : | Recombinant Interleukin-4 protein, fused to His-tag at N-terminus, was expressed inE.coliand was purified by conventional chromatography techniques, after refolding of theisolated inclusion bodies in a renaturation buffer. MW = 17.2kDa (150aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL4-137H |
Description : | Interleukin-4 (IL-4) is a pleiotropic cytokine that has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of naïve helper T-cell to Th2 cells. Interleukin-4 is a co-stimulator of DNA-synthesis and is induces the expression of class II MHC molecules on resting B-cells. It also enhances both secretion and cell surface expression of IgE and IgG1. |
Source : | E.coli. |
Amino Acid Sequence : | MGSSHHHHHH SSGLVPRGSH MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1ug of protein (determined by LAL method). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | IL4 interleukin 4 [ Homo sapiens ] |
Synonyms : | IL4; interleukin 4; BSF1; IL-4; BCGF1; BCGF-1; MGC79402; B-cell stimulatory factor 1; Interleukin-4; Lymphocyte stimulatory factor 1; Binetrakin; Pitrakinra; B-cell stimulatory factor 1; B_cell stimulatory factor 1 |
Gene ID : | 3565 |
mRNA Refseq : | NM_000589 |
Protein Refseq : | NP_000580 |
MIM : | 147780 |
UniProt ID : | P05112 |
Chromosome Location : | 5q31.1 |
Pathway : | Allograft rejection; Asthma; Autoimmune thyroid disease; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Hematopoietic cell lineage; Jak-STAT signaling pathway; cell receptor signaling pathway |
Function : | cytokine activity; growth factor activity; interleukin-4 receptor binding; protein binding |
Products Types
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IL4-2073R | Recombinant Rhesus Macaque IL4 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL4-1258S | Recombinant Sheep IL4 Protein, His-B2M/MYC-tagged | +Inquiry |
◆ Lysates | ||
IL4-001MCL | Recombinant Mouse IL4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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