Recombinant Human ENPP7, His-tagged

• Cat.No.: ENPP7-287
• Product Overview: Recombinant Human ENPP7 encoding the human ENPP7 (NP_848638.2) (Met1-Ser439) was fused with a C-terminal his tag. It was expressed inHuman Cells (HEK293).

Specification

• Cat. No.: ENPP7-287H
• Description: Ectonucleotide pyrophosphatase/ phosphodiesterase 7 (ENPP7), also known as alkaline sphingomyelinase (alk-Smase), is a member of nucleotide phosphodiesterase (NPP) family and is expressed in the intestines and humanbile. ENPP7 is a single-passtypeⅠmembrane protein,and islocalized at th esurface of the microvilla rmembrane in small lintestine enterocytes, as well as in endosome-like structures and in Golgicomplex.
• Molecular Mass: The secreted recombinant human ENPP7 comprises 429 amino acids with a predicted molecular mass of 49 kDa. As a result of glycosylation, rhENPP7 migrates as an approximately 55-60 kDa band in SDS-PAGE under reducing conditions.
• Source: Human Cells (HEK293).
• Predicted N Terminal: Ala 22.
• Purity: > 95% as determined by SDS-PAGE.
• Formulation: Supplied as a 0.2μm filtered solution of PBS, pH7.4.
• Stability: Samples are stable for up to twelve months from date of receipt -70℃.
• Endotoxin: < 1.0 EU per 1μg cytokine as determined by the LAL method.
• Reconstitution: Follow the instructions on the vial. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage and be used as soon as possible. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 [ Homo sapiens ]
• Synonyms: ENPP7; ectonucleotide pyrophosphatase/phosphodiesterase 7; MGC50179; ALK-SMase; alk-SMase; Ectonucleotide pyrophosphatase/phosphodiesterase family member 7;E-NPP7; NPP-7; Alkaline sphingomyelin phosphodiesterase; Intestinal alkaline sphingomyelinase; Alk-SMase; UNQ3077/PRO9912; EC 3.1.4.12;alkaline sphingomyelinase
• Gene ID: 339221
• mRNA Refseq: NM_178543
• Protein Refseq: NP_848638
• UniProt ID: Q6UWV6
• Chromosome Location: 17q25.3
• Pathway: Metabolic pathways; Sphingolipid metabolism
• Function: hydrolase activity; sphingomyelin phosphodiesterase activity