Embryonic Ectoderm Development
Cat.No. : | CBCRY07 |
- Specification
- Gene Information
- Related Products
Cat. No. : | CBCRY07 |
Background : | The crystal structure of EED in complex with a 30 residue peptide from EZH2 reveals that the peptide binds to the bottom of the WD-repeat domain of EED. The structural determinants of EZH2-EED interaction are present not only in EZH2 and EZH1 but also in its Drosophila homolog E(Z), suggesting that the recognition of ESC by E(Z) in Drosophila employs similar structural motifs. Structure-based mutagenesis identified critical residues from both EED and EZH2 for their interaction. |
Protein Classification : | gene regulation |
Structure Weight : | 45399.05 Da |
Polymer : | 1 |
Molecule : | Embryonic ectoderm development |
Chain Length : | 361 amino acids |
PDB ID : | 2QXV |
MMDB ID : | 59571 |
Source : | E.coli |
Method : | X-Ray Diffraction |
Resolution : | 1.82Å |
Reference : | Han, Z., Xing, X., Hu, M., Zhang, Y., Liu, P., Chai, J. (2007) Structural basis of EZH2 recognition by EED Structure 15: 1306-1315 |
Gene Name : | Eed |
Synonyms : | embryonic ectoderm development; ENSMUSG00000039373; l(7)5Rn; l7Rn5; lusk; OTTMUSP00000023294; lethal; Chr 7; Rinchik 5 |
Chromosome Location : | 7 |
Function : | chromatin binding; histone methyltransferase binding; protein binding |
Gene ID : | 14056 |
Products Types
◆ Recombinant Protein | ||
EED-2833H | Recombinant Human EED Protein, His (Fc)-Avi-tagged | +Inquiry |
EED-410H | Recombinant Human EED Protein, His-tagged | +Inquiry |
Eed-2732M | Recombinant Mouse Eed Protein, Myc/DDK-tagged | +Inquiry |
EED-1206R | Recombinant Rhesus Macaque EED Protein, His (Fc)-Avi-tagged | +Inquiry |
EED-1207H | Recombinant Human EED Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
EED-531HCL | Recombinant Human EED cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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