"RLN3" Related Products


Recombinant Human Relaxin 3

Cat. No.: RLN3-115H
Product Overview: Recombinant Human Relaxin-3 produced inE.coliis a 5.5 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 27 amino acid B-chain.
Description: Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as "somatostatin-like" or "angiotensin-like" peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an "orphan" G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats.
Source: E.coli.
Purity: 98 % (SDS-PAGE, HPLC).
Endotoxin Level: < 0.1 ng per ug of Relaxin-3.
Stabilizer: None.
Formulation: Lyophilized.
Biological Activity: Data not available!
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20℃. Reconstituted Relaxin-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20℃. Avoid repeated freeze-thaw cycles.
Gene Name: RLN3 relaxin 3 [ Homo sapiens ]
Synonyms: RLN3; relaxin 3; H3; RXN3; ZINS4; insl7; 19p13.2; relaxin 3 (H3); Relaxin-3; Prorelaxin H3; Insulin-like peptide INSL7; Insulin-like peptide 7; Relaxin-3 B chain;Relaxin-3 A chain; UNQ6188/PRO20213
Gene ID: 117579
mRNA Refseq: NM_080864
Protein Refseq: NP_543140
MIM: 606855
UniProt ID: Q8WXF3
Chromosome Location: 1q21
Function: G-protein-coupled receptor binding; hormone activity

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