Recombinant Human Relaxin 3
Cat.No. : | RLN3-115H |
Product Overview : | Recombinant Human Relaxin-3 produced inE.coliis a 5.5 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 27 amino acid B-chain. |
- Specification
- Gene Information
- Related Products
Cat. No. : | RLN3-115H |
Description : | Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as "somatostatin-like" or "angiotensin-like" peptide receptor, and also binds specifically to the LGR7 receptor, previously identified as an "orphan" G protein coupled receptor. Signaling by Relaxin-3 through its target receptors is, most likely, part of a CNS processing system, activated in response to signaling by neuropeptides and other factors. Intracerebroventricular injections of Relaxin-3 have been shown to cause a significant increase of food intake and body weight in Wistar rats. |
Source : | E.coli. |
Purity : | 98 % (SDS-PAGE, HPLC). |
Endotoxin Level : | < 0.1 ng per ug of Relaxin-3. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biological Activity : | Data not available! |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -20℃. Reconstituted Relaxin-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20℃. Avoid repeated freeze-thaw cycles. |
Gene Name : | RLN3 relaxin 3 [ Homo sapiens ] |
Synonyms : | RLN3; relaxin 3; H3; RXN3; ZINS4; insl7; 19p13.2; relaxin 3 (H3); Relaxin-3; Prorelaxin H3; Insulin-like peptide INSL7; Insulin-like peptide 7; Relaxin-3 B chain;Relaxin-3 A chain; UNQ6188/PRO20213 |
Gene ID : | 117579 |
mRNA Refseq : | NM_080864 |
Protein Refseq : | NP_543140 |
MIM : | 606855 |
UniProt ID : | Q8WXF3 |
Chromosome Location : | 1q21 |
Function : | G-protein-coupled receptor binding; hormone activity |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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