"Il11" Related Products

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Recombinant Murine Interleukin 11

Cat. No.: Il11-161M
Product Overview: Recombinant Murine IL-11 produced inE.coliis a 19.1 kDa protein consisting of 179 amino acid residues.
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.
Source: E.coli.
Purity: > 98% by SDS-PAGE.
Endotoxin Level: < 0.1 ng per μg of IL-11.
Stabilizer: None.
Formulation: Lyophilized.
Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg.
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20℃. Reconstituted IL-11 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20℃. Avoid repeated freeze-thaw cycles.
Gene Name: Il11 interleukin 11 [ Mus musculus ]
Synonyms: Il11; interleukin 11; IL-11
Gene ID: 16156
mRNA Refseq: NM_008350
Protein Refseq: NP_032376
UniProt ID: P47873
Chromosome Location: 7 2.0 cM
Pathway: Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Jak-STAT signaling pathway
Function: cytokine activity; interleukin-11 receptor binding; growth factor activity

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