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Recombinant Human Zinc Finger, GATA-like Protein 1

Cat.No. : ZGLP1-941H
Product Overview : Recombinant human GLP-1 produced inE.coliis a 3.3 kDa consisting of 31 amino acid residues.
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  • Gene Information
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Cat. No. : ZGLP1-941H
Description : GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
Source : E.coli.
Purity : 98 % (SDS-PAGE, HPLC).
Endotoxin level : < 0.1 ng per ug of GLP-1.
Stabilizer : None.
Formulation : Lyophilized.
Biologically Activity : Data not available!
Stability : The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name : ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ]
Synonyms : ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1
Gene ID : 100125288
mRNA Refseq : NM_001103167
Protein Refseq : NP_001096637
MIM : 611639
UniProt ID : P0C6A0
Chromosome Location : 19p13.2
Function : metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is the expression level of ZGLP1 protein affected by environmental factors? 12/08/2022

Yes, the expression level of ZGLP1 protein may be affected by environmental factors such as nutritional status, inflammatory response, oxidative stress, etc. These factors may affect the expression of ZGLP1 protein by regulating gene transcription and translation levels.

What is the distribution of ZGLP1 protein in humans? 10/30/2022

ZGLP1 protein is mainly distributed in the liver, kidney, heart, skeletal muscle and other tissues of the human body.

What is the potential of ZGLP1 protein in drug discovery? 12/03/2021

Due to the important role of ZGLP1 protein in cell growth and differentiation, it may become an important target for drug discovery. Drugs targeting the ZGLP1 protein may have the potential to modulate cell growth and differentiation.

How can I increase the expression level or activity of ZGLP1 protein? 11/09/2021

There is currently no way to directly increase the expression level or activity of ZGLP1 protein. However, its expression levels or activity can be affected by modulating the signal transduction pathways associated with it.

Can the expression level of ZGLP1 protein be used as a biomarker for disease diagnosis or prognosis? 03/31/2021

The current research on the expression level of ZGLP1 protein as a biomarker for disease diagnosis or prognosis is insufficient and needs to be further validated.

What are the current challenges and controversies in the research on ZGLP1 protein? 10/13/2020

There are still some challenges and controversies in the current research on ZGLP1 protein, including its specific mechanism of action in different cell types and disease states, its interaction with other molecules, and the optimal treatment.

Customer Reviews (3)

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Reviews
03/23/2021

    The results of multiple experiments are highly consistent and the reproducibility is particularly good.

    03/08/2021

      Very good product, great for western-blot.

      10/18/2020

        It can be dissolved in many types of reagents for easy handling.

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