Recombinant Human Zinc Finger, GATA-like Protein 1

• Cat.No.: ZGLP1-941H
• Product Overview: Recombinant human GLP-1 produced inE.coliis a 3.3 kDa consisting of 31 amino acid residues.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
• Purity: 98 % (SDS-PAGE, HPLC).
• Endotoxin level: < 0.1 ng per ug of GLP-1.
• Stabilizer: None.
• Formulation: Lyophilized.
• Biologically Activity: Data not available!
• Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ]
• Synonyms: ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1
• Gene ID: 100125288
• mRNA Refseq: NM_001103167
• Protein Refseq: NP_001096637
• MIM: 611639
• UniProt ID: P0C6A0
• Chromosome Location: 19p13.2
• Function: metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding