Recombinant Human Zinc Finger, GATA-like Protein 1 ZGLP1-941H

Cat. No.:	ZGLP1-941H
Product Overview:	Recombinant human GLP-1 produced inE.coliis a 3.3 kDa consisting of 31 amino acid residues.
Description:	GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2.
Source:	E.coli.
Purity:	98 % (SDS-PAGE, HPLC).
Endotoxin level:	< 0.1 ng per ug of GLP-1.
Stabilizer:	None.
Formulation:	Lyophilized.
Biologically Activity:	Data not available!
Stability:	The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles.

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Gene Name:	ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ]
Synonyms:	ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1
Gene ID:	100125288
mRNA Refseq:	NM_001103167
Protein Refseq:	NP_001096637
MIM:	611639
UniProt ID:	P0C6A0
Chromosome Location:	19p13.2
Function:	metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding