Recombinant Human Zinc Finger, GATA-like Protein 1
Cat.No. : | ZGLP1-941H |
Product Overview : | Recombinant human GLP-1 produced inE.coliis a 3.3 kDa consisting of 31 amino acid residues. |
- Specification
- Gene Information
- Related Products
Cat. No. : | ZGLP1-941H |
Description : | GLP-1 is a proglucagon-derived peptide hormone secreted primarily by intestinal L cells during feeding. Its major physiological function is stimulation of pancreatic β-cells to release appropriate amounts of insulin after glucose absorption. Other biological actions exhibited by GLP-1 include suppression of plasma glucagons levels, inhibition of gastric motility, and promotion of satiety. The secretion of GLP-1 from intestinal L cells is stimulated by nutrients, hormones, and neural inputs. On the other hand, insulin has been reported to inhibit GLP-1 release, indicating that a feedback loop mechanism regulates GLP-1 secretion. In addition to being the precursor of GLP-1, proglucagon, whose primary structure is highly conserved in mammalian species, is also the precursor for other members of the glucagon family of peptide hormones including glicentin-related pancreatic peptide (GRPP), glucagons, and GLP-2. |
Source : | E.coli. |
Purity : | 98 % (SDS-PAGE, HPLC). |
Endotoxin level : | < 0.1 ng per ug of GLP-1. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biologically Activity : | Data not available! |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GLP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze-thaw cycles. |
Gene Name : | ZGLP1 zinc finger, GATA-like protein 1 [ Homo sapiens ] |
Synonyms : | ZGLP1; zinc finger, GATA-like protein 1; GLP1; GLP-1; FLJ39511; FLJ39703; GATA like protein 1 |
Gene ID : | 100125288 |
mRNA Refseq : | NM_001103167 |
Protein Refseq : | NP_001096637 |
MIM : | 611639 |
UniProt ID : | P0C6A0 |
Chromosome Location : | 19p13.2 |
Function : | metal ion binding; sequence-specific DNA binding; transcription factor activity; transcription repressor activity; zinc ion binding |
Products Types
◆ Recombinant Protein | ||
ZGLP1-10375M | Recombinant Mouse ZGLP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ZGLP1-167H | Recombinant Human Zinc Finger, GATA-Like Protein 1 | +Inquiry |
ZGLP1-4394Z | Recombinant Zebrafish ZGLP1 | +Inquiry |
ZGLP1-19171M | Recombinant Mouse ZGLP1 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, the expression level of ZGLP1 protein may be affected by environmental factors such as nutritional status, inflammatory response, oxidative stress, etc. These factors may affect the expression of ZGLP1 protein by regulating gene transcription and translation levels.
ZGLP1 protein is mainly distributed in the liver, kidney, heart, skeletal muscle and other tissues of the human body.
Due to the important role of ZGLP1 protein in cell growth and differentiation, it may become an important target for drug discovery. Drugs targeting the ZGLP1 protein may have the potential to modulate cell growth and differentiation.
There is currently no way to directly increase the expression level or activity of ZGLP1 protein. However, its expression levels or activity can be affected by modulating the signal transduction pathways associated with it.
The current research on the expression level of ZGLP1 protein as a biomarker for disease diagnosis or prognosis is insufficient and needs to be further validated.
There are still some challenges and controversies in the current research on ZGLP1 protein, including its specific mechanism of action in different cell types and disease states, its interaction with other molecules, and the optimal treatment.
Customer Reviews (3)
Write a reviewThe results of multiple experiments are highly consistent and the reproducibility is particularly good.
Very good product, great for western-blot.
It can be dissolved in many types of reagents for easy handling.
Ask a Question for All ZGLP1 Products
Required fields are marked with *
My Review for All ZGLP1 Products
Required fields are marked with *
Inquiry Basket