|Cat. No. :
|Product Overview :
||Recombinant human ICAM-1 produced inCHO cellsis a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Monomeric glycosylated ICAM-1 migrates at an apparent molecular weight of approximately 72.0-80.0 kDa by SDS-PAGE analysis under reducing conditions.
||ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain.
||>98 % (SDS-PAGE, HPLC).
|Endotoxin Level :
||< 0.1 ng per ug of ICAM-1.
||The lyophilized protein is stable for at least 2 years from date of receipt at -20℃. Reconstituted ICAM-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20℃.