Eukaryotic translation initiation factor 3 subunit K

• Cat.No.: CBCRY12

Specification

• Cat. No.: CBCRY12
• Background: eIF3k, the smallest subunit of eukaryotic initiation factor 3 (eIF3), interacts with several other subunits of eIF3 and the 40 S ribosomal subunit. eIF3k is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. Interestingly, eIF3k does not exist in some species of yeast. Thus, eIF3k may play a unique regulatory role in higher organisms.
• Protein Classification: Biosynthetic protein
• Structure Weight: 26532.46 Da
• Polymer: 1
• Molecule: Eukaryotic translation initiation factor 3 subunit 11
• Chain Length: 250 amino acids
• PDB ID: 1RZ4
• MMDB ID: 29334
• Source: E.coli
• Method: X-Ray Diffraction
• Resolution: 2.1?
• Ligand Chemical Component: sulfate ion
• Reference: Wei, Z., Zhang, P., Zhou, Z., Cheng, Z., Wan, M., Gong, W.(2004) Crystal structure of human eIF3k, the first structure of eIF3 subunitsJ.Biol.Chem.279: 34983-34990

Gene Information

• Gene Name: EIF3K
• Synonyms: ARG134; EIF3-p28; EIF3S12; HSPC029; M9, MSTP001; PLAC-24,;PLAC24; PRO1474; PTD001; Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 protein; eIF-3 p25; eIF-3 p28; eukaryotic translation initiation factor 3, subunit K; muscle specific; ptd001
• UniProt ID: Q9UBQ5
• Gene ID: 27335
• Chromosome Location: 19q13.2
• Function: translation initiator factor activity; protein binding; ribosome binding