Eukaryotic translation initiation factor 3 subunit K CBCRY12

Eukaryotic translation initiation factor 3 subunit K

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Eukaryotic translation initiation factor 3 subunit K

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Cat. No. : CBCRY12
Background : eIF3k, the smallest subunit of eukaryotic initiation factor 3 (eIF3), interacts with several other subunits of eIF3 and the 40 S ribosomal subunit. eIF3k is conserved among high eukaryotes, including mammals, insects, and plants, and it is ubiquitously expressed in human tissues. Interestingly, eIF3k does not exist in some species of yeast. Thus, eIF3k may play a unique regulatory role in higher organisms.
Protein Classification : Biosynthetic protein
Structure Weight : 26532.46 Da
Polymer : 1
Molecule : Eukaryotic translation initiation factor 3 subunit 11
Chain Length : 250 amino acids
PDB ID : 1RZ4
MMDB ID : 29334
Source : E.coli
Method : X-Ray Diffraction
Resolution : 2.1?
Ligand Chemical Component : sulfate ion
Reference : Wei, Z., Zhang, P., Zhou, Z., Cheng, Z., Wan, M., Gong, W.(2004) Crystal structure of human eIF3k, the first structure of eIF3 subunitsJ.Biol.Chem.279: 34983-34990
Gene Name : EIF3K
Synonyms : ARG134; EIF3-p28; EIF3S12; HSPC029; M9, MSTP001; PLAC-24,;PLAC24; PRO1474; PTD001; Eukaryotic translation initiation factor 3 subunit 12; Muscle-specific gene M9 protein; eIF-3 p25; eIF-3 p28; eukaryotic translation initiation factor 3, subunit K; muscle specific; ptd001
UniProt ID : Q9UBQ5
Gene ID : 27335
Chromosome Location : 19q13.2
Function : translation initiator factor activity; protein binding; ribosome binding

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