Recombinant Human Prospero Homeobox 1

• Cat.No.: PROX1-958H
• Product Overview: Recombinant Human prospero homeobox 1 produced inE.coliwas not tested for activity and can be used as positive control e.g. in Western analysis. MW=25 kDa.

Specification

• Cat. No.: PROX1-958H
• Description: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.
• Source: E.coli.
• Purity: >95%by SDS-PAGE and visualised by silver stain.
• Endotoxin level: <0.1ng/μg of Prox-1.
• Stabilizer: None.
• Buffer: PBS.
• Formulation: Lyophilized.
• Reconstitution: We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4℃ for 1 week or -20℃ for future use.
• Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted Prox-1 should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: PROX1 prospero homeobox 1 [ Homo sapiens ]
• Synonyms: PROX1; prospero homeobox 1; prospero-related homeobox 1; Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1
• Gene ID: 5629
• mRNA Refseq: NM_002763
• Protein Refseq: NP_002754
• MIM: 601546
• UniProt ID: Q92786
• Chromosome Location: 1q41
• Function: DBD domain binding; LBD domain binding; RNA polymerase II transcription factor activity, enhancer binding; ligand-dependent nuclear receptor binding; promoter binding; protein binding; transcription corepressor activity