"GDF6" Related Products

Expand

Recombinant Human Growth Differentiation Factor 6

Cat. No.: GDF6-19H
Product Overview: Recombinant HumanGDF6 produced inE.coliwas a 27.0kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.This 27.5kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7kDa.
Description: BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
Source: E.coli.
Purity: >95% by SDS-PAGE.
Endotoxin Level: <0.1ng/μg of BMP-13.
Stabilizer: None.
Formulation: Lyophilized.
Biologically Activity: The ED50was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0μg/ml.
Reconstitution: The human BMP-13 should be reconstituted in water to a concentration of 0.1-1.0mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human BMP-13 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Gene Name: GDF6 growth differentiation factor 6 [ Homo sapiens ]
Synonyms: GDF6; growth differentiation factor 6; KFSL; KFS; GDF16; SGM1; BMP13; CDMP2; MCOP4; SCDO4; MGC158100; MGC158101; Growth/differentiation factor 6; Growth/differentiation factor 16
Gene ID: 392255
mRNA Refseq: NM_001001557.2
Protein Refseq: NP_001001557.1
MIM: 601147
UniProt ID: Q6KF10
Chromosome Location: 8q22.1
Pathway: Cytokine-cytokine receptor interaction; TGF-beta signaling pathway
Function: cytokine activity; growth factor activity

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.