"BMP4" Related Products

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Recombinant Human Bone Morphogenetic Protein 4

Cat. No. : BMP4-20H
Product Overview : Recombinant human BMP-4 expressed inHeLa cellswas a 31-36kDa homodimeric glycoprotein.
Description : Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder fibrodysplasia ossificans progressiva.
Source : HeLa cells.
Purity : >97% by SDS-PAGE and HPLC analysis.
Endotoxin Level : <0.1ng/μg of BMP-4.
Stabilizer : None.
Formulation : Lyophilized.
Biologically Activity : Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
Stability : The lyophilized protein is stable for at least 2 years from date of receipt at -20oC. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20oC. Avoid repeated freeze-thaw cycles!
PDB rendering based on 1reu. :

Gene Name : BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
Synonyms : ZYME; BMP2B; BMP2B1; DVR4; MCOPS6; BMP-2B; BMP-4; Bone morphogenetic protein 4 precursor; bone morphogenetic protein 2B; bone morphogenetic protein 4; BMP4
Gene ID : 652
mRNA Refseq : NM_001202
Protein Refseq : NP_001193
MIM : 112262
UniProt ID : P12644
Chromosome Location : 14q22-q23
Function : cytokine activity; growth factor activity; heparin binding; protein binding; signal transducer activity

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