"BMP4" Related Products

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Recombinant Human Bone Morphogenetic Protein 4

Cat. No.: BMP4-20H
Product Overview: Recombinant human BMP-4 expressed inHeLa cellswas a 31-36kDa homodimeric glycoprotein.
Description: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder fibrodysplasia ossificans progressiva.
Source: HeLa cells.
Purity: >97% by SDS-PAGE and HPLC analysis.
Endotoxin Level: <0.1ng/μg of BMP-4.
Stabilizer: None.
Formulation: Lyophilized.
Biologically Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20oC. Reconstituted BMP-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20oC. Avoid repeated freeze-thaw cycles!
Gene Name: BMP4 bone morphogenetic protein 4 [ Homo sapiens ]
Synonyms: ZYME; BMP2B; BMP2B1; DVR4; MCOPS6; BMP-2B; BMP-4; Bone morphogenetic protein 4 precursor; bone morphogenetic protein 2B; bone morphogenetic protein 4; BMP4
Gene ID: 652
mRNA Refseq: NM_001202
Protein Refseq: NP_001193
MIM: 112262
UniProt ID: P12644
Chromosome Location: 14q22-q23
Function: cytokine activity; growth factor activity; heparin binding; protein binding; signal transducer activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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